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GLP-1 receptor agonists have transformed weight management and diabetes treatment

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Semaglutide and tirzepatide are GLP-1 receptor agonists (tirzepatide also targeting GIP), mimicking gut hormones that regulate satiety and blood sugar a well-established pathway with extensive human data

Melanocytes melanin production is altered by these receptors

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While both isoforms have been detected in the human testes, as well as in the testes of other mammals, GH-V was shown to be predominantly expressed form in human testes (86, 87)