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Interestingly, when both inhibitors are co-administered the result is similar to each administered independently, suggesting that other signaling proteins may also contribute to protection (data not shown)

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Furthermore, combined treatment of schistosomula with TGR dsRNA and AF showed significant synergistic effects, suggesting that both act by decreasing TGR activity

doi: [Elsevier] [AJOG] Pogribna, M., Melnyk, S., Pogribny, I., Chango, A., Yi, P., & James, S