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This helps explain why payer coverage restrictions for GLP-1s used for obesity continue to be a hurdle for patients who seek access

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T1DM is characterized by imbalances in Th17/Treg, Th1, and Th2 immune responses

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Variants in GLP1R, GIPR, FTO, and MC4R genes may help provide context for your provider's clinical decision-making around whether tirzepatide is appropriate and at what dosing strategy to begin

Moreover, for patients taking other oral combination drugs, the additional use of injectable drugs results in low therapeutic adherence and compliance [15]