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Eligible individuals had a body mass index (BMI) above 30 kg/m, did not exercise regularly in the previous six months, did not have a history of endocrine or cardiovascular diseases, and did not smoke or drink alcohol

In fact research has found that low B12 is common in those with insulin resistance and abdominal obesity in those with PCOS

Troubleshooting insufficient weight loss If weight loss stalls despite being at target doses, evaluate compliance first

[DOI] [PubMed] [Google Scholar] 29.Han P, Qin Z, Tang J, Xu Z, Li R, Jiang X, Yang C, Xing Q, Qi X, Tang M, et al

This powerful antioxidant becomes a cofactor for dozens of detox enzymes that neutralize damaging free radicals

The GPX4 encoded enzyme, GPx4, is localized to the intestines and is an extracellular enzyme as well