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Hsd3b1 mRNA levels were significantly higher in LCs treated with 10 g/L (0.03 IU/L) rhGH but Hsd3b1 mRNA levels of 50 g/L (0.15 IU/L) rhGH treated LC were significantly lower than those of controls

The response to acute focal TBI with tissue damage develops in the following phases: (i) cell death and inflammation, (ii) cell proliferation, tissue replacement with fibrotic scar and wound closure and (iii) tissue remodelling and neuroplasticity aimed at restoration and functional compensation 26,160 (Fig