Protein aggregation-driven UPS impairment in sporadic NDDs In addition to genetic mutations, UPS dysfunction is also a defining feature of sporadic NDDs, where aggregation-prone proteins directly impair proteasomal function
Wolfe, R.R., Goodenough, R.D., Burke, J.F., et al., Response of Protein urea kinetics in burn patients to different levels of protein intake, Ann
The article ends with a sentence like during B12 treatment, there is no need to check the B12 concentration in the blood, as this is supposed to be high. And 130 pmol/l is NOT high
Vance and Melwani Daswani, 2020
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