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Resetting the autoreactive immune system with a therapeutic peptide in lupus

No single peptide dominates the literature research is split across four categories by mechanism: incretin-pathway compounds like GLP-3 RT, fragment-based lipolytic peptides like AOD-9604, growth-hormone-releasing analogs like Tesamorelin, and secretagogue pairings like CJC-1295/Ipamorelin

EFSA NDA Panel (EFSA Panel on Dietetic Products, Nutrition and Allergies), 2015

Hepatic Steatosis : Recently, a sub-study of the phase 3 clinical trial SURPASS-3 showed that, among patients receiving metformin and/or SGLT2 inhibitors, the addition of tirzepatide (10 or 15 mg) as compared to insulin degludec was able to significantly reduce hepatic fat content (evaluated by magnetic resonance) after 52 weeks of treatment