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not intended for use in diabetic models

Compared with metformin IR (immediate-release) or metformin XR (extended-release), the bioavailability of metformin DR is lower, yet its glucose-lowering efficacy is similar, despite lower systemic metformin exposure [15]

"This is a medicine that's already available, both in diabetes clinics and now in renal clinics, so I would hope the uptake would start pretty quickly," Gough said, adding that he hopes the confidence that comes with the data behind this approval will aid clinicians who are making daily decisions about how and when to use different treatments

In Gilbert, compounded GLP-1 medications generally cost $200 to $450 monthly, while brand-name Wegovy or Mounjaro can run $1,000 or more without insurance

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