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Topical treatments are less effective

We further examine how unresolved issues in manufacturing scale-up, prediction of in vivo behavior, safety assessment, biological heterogeneity and clinical value define the space between experimental constructs and clinical application [18, 20, 21, 24]

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The biosorption efficiency recorded was 97.90% achieved at dose of 4.48 g/L, pH of 6.62 and concentration of 29.72 mg/L for the optimum conditions

The mechanisms associated with these events and their role in cardiovascular disease are outlined below