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Okuda K, Dang H, Kobayashi Y, Carraro G, Nakano S, Chen G, et al

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doi: 10.1073/pnas.96.26.14843

Ischemic cells compensate for reduced oxygen delivery by increasing anaerobic glycolysis, leading to acidosis as well as glucose derivatives that promote signaling related to oxidative stress and inflammation [38, 57, 62]

Quick Answer: Dulaglutide and once-weekly exenatide appear to have the lowest rates of nausea amongst GLP-1 receptor agonists, with approximately 1224% of patients affected compared with higher rates seen with other formulations