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In contrast, late-phase severe patients showed limited evidence of coordinated recovery, instead exhibiting persistent broad suppression of mtDNA-encoded OXPHOS genes across nearly all PBMC subsets, with only isolated exceptions, such as MT-CO2 and MT-CO3

Lustig RH, Pfaff DW, Fishman J: Opioidergic modulation of the oestradiol-induced LH surge in the rat: roles of ovarian steroids

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