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AAV Mediated Exendin-4 Gene Transfer to Salivary Glands to Protect Subjects from Diabetes or Obesity

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while all three treated groups had benefits as assessed by looking at liver fat area and triglycerides, the Sema + -MSTN/-ActA combination (which had the largest decreases in overall body fat composition) also had the largest benefits in terms of these liver measures (Fig

Methods: Using targeted metabolomic profiling of lung tissues collected on day 5 from two distinct murine models of lung inflammationlipopolysaccharide (LPS)-induced and papain-inducedwe identified carnosine as a commonly downregulated metabolite in both models

TABLE 4 Multimodal technology integration optimizing translational applications of zebrafish models in plant-derived anti-inflammatory research