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Deficiency of these two genes reduces the uptake of extracellular fatty acids, impairs fatty acid -oxidation and mitochondrial oxidative metabolism, and adversely affects the long-term survival of skin tissue-resident memory T cells following viral infection [53]

Previously, the diagnosis of NAFLD was exclusionary, requiring individuals to have signs of liver steatosis in the absence of secondary causes such as alcohol intake, utilization of certain medications, or previously recognized liver disease 19

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