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The activation of the NLRP3 inflammasome mediates the cleavage of caspase-1 and the secretion of the IL-1 proinflammatory cytokine, ultimately inducing cell death through a process known as pyroptosis
Trends Neurosci 37(8):433442
Redness, swelling, or persistent tenderness at either site
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PubMed Duzel, A., Vlainic, J., Antunovic, M., Malekinusic, D., Vrdoljak, B., Samara, M., Gojkovic, S., Krezic, I., Vidovic, T., Bilic, Z., Sjekavica, I., Djuzel, A.R., Knezevic, M., Sever, A.Z., Lojo, N., Kokot, A., Sever, M., Drmic, D., Seiwerth, S., Sikiric, P