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(i) In a randomized, double-blind controlled trial conducted by Adams et al., reductions in measures of the severity of autism were associated with the difference in urinary excretion of toxic metals before and following treatment with DMSA, demonstrating both a significant positive association between the severity of autism and the body burden of toxic metals, and efficacy of reduction of this body burden in improving symptoms [96]

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Each pulse typically lasts 23 hours and occurs 68 times per 24-hour cycle in healthy adults

Additional file 2: Supplementary Figure 2

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