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A small clinical trial showed a 2 to 10-fold increase in GH levels lasting up to 6 days after a single injection (Teichman et al., J Clin Endocrinol Metab 2006)

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However, high doses may cause excessive bleeding and oxidative stress

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The CJC-1295 + ipamorelin layer is added to push GH and IGF-1 (a downstream growth signal) higher, which supports lean-tissue retention, recovery, sleep quality, and connective-tissue repair during the deficit