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Slowly increasing the dose of a GLP-1 medication allows the body time to adjust to the changes that are occurring, especially the slowing of gastric motility, says Currier, So the key to avoiding the nausea as much as possible is to take the titration phase slowly and allow the body time to acclimate appropriately. If someone increases the dose too quickly or overdoses, theyre more likely to experience severe nausea
These involve visible skin changes rather than altered sensation
For example, healthcare systems will need to decide how, when and for what indications they will reimburse new weight-loss drugs
Future of Obesity Treatment: Can Semaglutide Lead the Way
Endocrinology (2012) 153:578295
Eli Lilly is studying retatrutide in several phase-3 clinical trials for obesity, type-2 diabetes, knee osteoarthritis pain, moderate-to-severe obstructive sleep apnea, chronic low back pain, cardiovascular and renal outcomes, and metabolic dysfunction-associated steatosis liver disease
