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Investigated in peer-reviewed preclinical research for its role in cellular signaling, metal-ion interaction pathways, extracellular matrix modeling, and gene expression studies

The research is much more focused on healthy aging and supporting long-term brain health

They act on gut-hormone pathways that regulate appetite, gastric emptying, blood sugar, and energy balance

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Another study found that decreased expression of system Xc and GPX4 was noted in kidney biopsy samples from DM patients compared to non-DM patients