High-dose oral supplementation may be another treatment option, because consuming 1,000 g (1 mg) per day of vitamin B 12 orally should result in the absorption of about 10 g/day (1% of dose) by passive diffusion
If left untreated, a deficit in vitamin B12 can cause significant harm to the brain, increasing the chance of death
Another form of renal toxicity, generally associated with NSAIDs, is seen in patients with prerenal conditions leading to the reduction in renal blood flow or blood volume, where the renal prostaglandins have a supportive role in maintaining renal perfusion
Store in cool, dry place
* Nerve damage * Blood clots Very rare side effects (may affect up to 1 in 10,000 people): * Cardiac arrest **Important Information:** * This is not an exhaustive list
Similarly, suboptimal compliance with other medications may lead to suboptimal treatment outcomes, prolonged recovery times, and drug resistance development