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2.3 Gene-related effect 2.3.1 APOL1 gene variant High kidney disease risk of Africa has been linked to APOL1 high-risk alleles

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Randomized, double-blind, placebo-controlled crossover studies in both insulin-treated type 2 diabetes patients and obese non-diabetic subjects have demonstrated significant reductions in ad libitum energy intake following pramlintide administration

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