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Quick reference: retatrutide dosage chart This chart reflects the escalation schedule used in Phase 2 and Phase 3 clinical trials: Standard titration protocol (2mg start 12mg target) Alternative protocols by target dose Target: 8 mg maintenance Target: 4 mg maintenance Key principle: Start low, go slow
3 Because postprandial hyperglycemia affects A1C to a greater degree than fasting hyperglycemia, the closer a patient is to the A1C goal, GLP-1 receptor agonists provide a viable treatment option to target postprandial glucose excursions due to their glucose-dependent effects on insulin secretion
Stopping GLP-1R agonists preoperatively may lead to worsened glycaemia and metabolic instability
Yes, absolutely!
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doi: 10.1016/j.clp.2017.10.007 29 ShiYAvatapalleHBSkaeMSPadidelaRNewbouldMRigbyLet al
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