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Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom

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Within days to weeks of stopping treatment, patients generally experience return of appetite to pre-treatment levels, faster gastric emptying, and loss of the medication's effects on satiety signaling

3.3 Development of unimolecular agents targeting both GIPR and GLP-1R The anti-obesity effects of GIPR antagonism antibody, both alone and in combination with GLP-1RAs, have been demonstrated in preclinical models of mice and monkeys (68, 73)

If you do try a patch, be sure to log weight, blood sugar, side effects, and energy levels so you can see if it is doing anything at all