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4.2.4 Lactic acid bacteria metabolites Lactic acid bacteria produce various metabolites, including 1,3-diaminopropane (DAP), reuterin, and 5-methoxyindoleacetic acid (5-MIAA)

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While adiponectin functions as an insulin sensitizer with anti-inflammatory and anti-fibrotic effects, leptin promotes energy homeostasis but also exerts pro-inflammatory and pro-fibrotic actions [21]

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Their results demonstrated that SOD supplementation significantly improved renal function by reducing serum creatinine and neutrophil gelatinase-associated lipocalin (NGAL) levels (Ismy et al., 2022)