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Meanwhile, a number of researchers elsewhere had also begun to uncover evidence pointing to a relationship between hormones produced in the intestine and pancreatic islets

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Previous research has demonstrated that GLP-1R knockout (KO) mice exhibit higher basal blood glucose concentrations compared to wild-type (WT) mice [186], along with impaired cerebral responses to exogenous glucose [187]

Additionally, for diabetic patients, the difficulty in managing blood sugar levels can lead to acute complications such as diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemic state (HHS), both of which can be fatal if not promptly treated

What dietary approach will best support maintenance during this transition

Regular GLP-1 treatment monitoring with your doctor is vital to ensure the medication is working safely and effectively for your body over the long term