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doi: 10.1111/nyas.14211 56 DruckerDJHolstJJ

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Clinical Evidence: Semaglutide's Impact on Metabolic Health The SUSTAIN trial series demonstrated that semaglutide reduces HbA1c (3-month average blood sugar) by 1.52.0% in people with type 2 diabetes, compared to 0.50.8% for older insulin therapies

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Most patients find this balanced approach sustainable, since total restriction often leads to unsustainable binge-restriction cycles