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There is some evidence that the diabetes drug metformin (Glucophage) may reduce vitamin B12 absorption when used for several years

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It may provoke neuropathy symptoms at first

Anti-inflammatory potential: Research suggests it may support the body's natural inflammatory response, which is critical for tissue healing and pain management

459,460 Neural stimulation has been reported to modify cortical excitability by affecting GABAergic function and causing LTP or LTD-like excitatory synaptic strength

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