Studies have shown that chronic hyperglycemia and recurrent hypoglycemia in patients with diabetes reduce brain network efficiency [108], impair hippocampal neurogenesis and memory [109], and lead to microstructural changes in white matter and reduced gray matter density [110]
Clinical trials have shown that weight loss with these medications typically ranges from 10-20% of body weight, depending on the specific agent and dosage, with tirzepatide showing the highest average weight reduction
Participants Eligible participants were adults aged 18 years or older who were scheduled to undergo an elective upper endoscopic procedure under monitored anesthesia care or moderate sedation
When To Consult A Doctor Contact your doctor if you have: Severe or persistent vomiting Severe diarrhoea Signs of dehydration, such as very low urine, dizziness, or extreme weakness Severe abdominal pain, especially if it spreads to the back Yellowing of the skin or eyes Fever with abdominal pain Inability to pass stool or gas Repeated low blood sugar episodes Sudden vision changes Palpitations or a racing heartbeat at rest Swelling of the face, lips, tongue, or throat Breathing difficulty Severe rash or itching New or worsening depression Suicidal thoughts Symptoms before planned surgery or endoscopy If you are scheduled for surgery or a procedure under anaesthesia, tell your healthcare team that you are using a GLP-1 medicine
I'm going to be careful about what I'm eating
Those who do not see weight loss with diet and lifestyle modifications can see increased weight loss by adding GLP-1
