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Pre-existing conditions such as diabetes require close monitoring throughout treatment

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Differences between groups were analyzed using a Students t test (two-group comparisons) or one-way analysis of variance (multiple-group comparisons) with Tukeys post-hoc multiple comparisons test

Cholestyramine, a bile salt resin, effectively alleviates cholestatic pruritus and is the first-line treatment even in cirrhosis due to its general tolerability and safety (4)

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