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Someone must have a BMI of over 35, or, for those who have a BMI between 30 to 35, they must also have one of the following (per CNN): Uncontrolled high blood pressure, prediabetes, a previous heart attack or stroke, blocked arteries in arms or legs with symptoms, chronic kidney disease at Stage 3a or higher, or diastolic heart failure

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CagriSema , combining semaglutide with cagrilintide (an amylin analog), represents another approach

10.1016/j.genhosppsych.2025.03.012 252 LatifiS.TamayolA.HabibeyR.SabzevariR.KahnC.GenyD.et al

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