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To assess human plasma PCSK5 levels following acute MI (AMI), plasma samples were collected from 28 AMI patients and 30 healthy controls (the detailed clinical profile of patients is summarised in Table S1)

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In February 2025, following review of the TRAVERSE data, the FDA removed the cardiovascular black-box warning from testosterone products

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[11] This indicates that animal reproduction studies have shown an adverse effect on the fetus, and there are no adequate, well-controlled studies in pregnant women