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J Physiol (2012) 590:291736.10.1113/jphysiol.2011.223800 138 PiMFaberPEkemaGJacksonPDTingAWangNet alIdentification of a novel extracellular cation-sensing G-protein-coupled receptor

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In the SURPASS-2 trial, which directly compared tirzepatide to semaglutide 1 mg for type 2 diabetes, nausea rates were 17-22% for tirzepatide across all three dose levels (5 mg, 10 mg, and 15 mg) versus 18% for semaglutide 1 mg

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