Furthermore, pre-synaptic and post-synaptic proteins, synaptophysin and PSD-95, which reflect synaptic disruption [122], were upregulated, neuronal excitability normalized, and intracellular calcium, a key regulator in metabolic dysfunction and progressive neuronal loss [123], was modulated [121]
Hercher, C., Chopra, V
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Participants with metabolic dysfunction-associated steatotic liver disease showed significant reductions in liver fat content with retatrutide treatment
Its also relatively inexpensive
According to IQVIA sales data for the 12month period ending August 2023 (MAT August 2023), the market for GLP-1 RA in India is estimated to be INR 259 crores, with an annual growth of 108% against the corresponding period last year (MAT August 2022)