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GLP-1-based therapies, such as GLP-1 receptor agonists, glucose-dependent insulinotropic polypeptide (GIP) receptor agonists, and dipeptidyl peptidase 4 (DPP-4) inhibitors, improve glucose control through various mechanisms including increased insulin secretion, slower gastric emptying, and reduced postprandial glucagon and food intake
On retatrutide, that same consumption pattern could produce BAC levels of 0.04-0.06%, which approaches or exceeds legal driving limits in many Canadian provinces
Garito T, Roubenoff R, Hompesch M, Morrow L, Gomez K, Rooks D, et al
Inflammopharmacology 30(3):10931105