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In patients undergoing coronary artery bypass and/or valvular surgery, intravenous NAC was shown to reduce the incidence of post-operative atrial fibrillation

The same comprehensive review also reported gas in 12% of participants in one of the analyzed cohorts, indicating that frequency can vary with study population and dosing, as reported in Comparative gastrointestinal adverse effects of GLP-1 receptor agonists and multi-target analogs in type 2 diabetes

But it does not yet appear that BNP testing is an any earlier warning system for MVD than auscultation

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Loading Protocols Some practitioners recommend a loading phase with higher initial doses followed by maintenance dosing