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Collagen and elastin related pathways Evidence sources : fibroblast and extracellular matrix studies, dermatology research Confidence : moderate on mechanisms Main caveats : more collagen in a dish does not automatically equal firmer or smoother skin in people

doi: 10.1053/jhep.2001.25885

Transdermal buprenorphine relieves neuropathic pain: a randomized, double-blind, parallel-group, placebo-controlled trial in diabetic peripheral neuropathic pain

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