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Conversely, Htr2a in mice is upregulated in UUO (LogFC = 3,26 [GSE87212]), while Htr3a (logFC = 2,32), Htr3b (logFC = 1,11) and Htr4 (logFC = 1,07) are downregulated in the murine model of UUO (GSE38117) and Htr2c is downregulated in the rat model of AKI induced by cisplatin (logFC = 1,31 [GSE37133])

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Because muscles burn more calories, increasing your strength training and focusing on building muscle can help raise your metabolism again and encourage your body to burn more fat