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95% CI [0.120.56]), as well as in adjudicated cardiovascular death or HF events
In a 1994 study, Mulder et al
Clinical Benefits: Supports red blood cell formation and helps prevent megaloblastic anaemia Essential for neurological function and nerve tissue health Plays a key role in DNA synthesis and cell metabolism Supports cognitive function, concentration, and mood regulation Assists in the conversion of homocysteine, supporting cardiovascular health Helps address fatigue and weakness associated with B12 deficiency For patients presenting with deficiency, a loading protocol is typically recommended: weekly injections for three weeks, followed by monthly injections for three months, then a maintenance injection every three months
The full therapeutic dose may not be reached until 16 to 20 weeks after initiation, which delays maximal efficacy but improves tolerability and treatment adherence
Badiou S, Cristol JP, Morena M, et al
