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Diet and exercise Participants were encouraged to maintain their normal dietary intake during an initial baseline week

Effect of weekly subcutaneous semaglutide vs daily liraglutide on body weight in adults with overweight or obesity without diabetes (STEP-8)

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Challenges for and current status of research into positive modulators of AMPA receptors

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The STEP (Semaglutide Treatment Effect in People with obesity) trials, particularly STEP 1, demonstrated not only significant weight loss but also improvements in cardiometabolic risk factors, including lipid parameters