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Briefly, during phase 1, cells were grown in Iscoves Modified Dulbecco medium (IMDM) with 15% fetal bovine serum (FBS), 15% human AB serum, 10 ng/mL interleukin-3, 50 ng/mL stem cell factor and 2 IU/mL erythropoietin (Sigma-Aldrich, St

While constraining, formulation strategies to enhance solubility, absorption, and systemic exposure have demonstrated rational and increasingly validated means to bridge the gap seen between mechanistic efficacy and clinical translation

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Desikan et al., 1998

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(ii) contrasting the exacerbation of the inflammatory response