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After 52 weeks of treatment, the proportion of participants in the oral semaglutide group achieving an A1C of less than 7.0% was 58.3% (treatment-policy estimand) and 62.8% (trial-product estimand), compared with 25.2% (treatment-policy estimand) and 28.3% (trial-product estimand) for the group receiving 100 mg of sitagliptin daily

Use of GLP-1 drugs for diabetes or obesity early in the first trimester of pregnancy, before a woman realizes she is pregnant, is not a cause for alarm, a large new data analysis suggests

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"The companies and the FDA, no one's identified an endgame with these drugs," Kessler says

2 In fact, according to Jaime Almandoz, MD, while more than 70 percent of U.S

doi: 10.1016/j.pharmthera.2006.11.007 52 BrandT