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Dynamic control of ATP not only ensures the functional activity of ion pumps and cellular flexibility, but also contributes to the availability of vasoregulatory ATP that can be exported when necessary, for example in hypoxia or upon RBC deformation in microvessels

Genetic polymorphisms, low-grade inflammation, poor diet, dysbiosis, and chronic disease, including diabetes and cardiovascular disease, may increase the conversion of TMA to TMAO

Our findings suggest that IF may offer a promising non-pharmacological intervention for managing RA in this population, potentially addressing both primary disease symptoms and associated metabolic complications 34

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