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Folate Insufficiency and Transport Abnormalities Despite the challenges for treating ASD, emerging data suggests that folate pathway abnormalities may play a role in the pathogenesis of ASD

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This substance is taken up by the tubular cells of the kidney and is reduced by cell glutathione to mesna

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To test this prediction, we mutated VadK-His422 to alanine, checked that VadK His422Ala was folded in a similar manner to VadK WT by circular dichroism (CD) (Appendix Fig