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The medications that will require prior authorization the process by which doctors must obtain approval from insurance companies before prescribing certain medication are used by people with severe disabilities, the groups say, including Multiple Sclerosis, traumatic brain injury, seizure disorders, arthritis and diabetes

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In some embodiments, local otic delivery of the auris formulations or compositions described herein allows for controlled release of active agents to auris structures and overcomes the drawbacks associated with systemic administration (e.g., low bioavailability of the drug in the endolymph or perilymph, variability in concentration of the drug in the external, middle and/or internal ear)

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