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So I knew that if we started talking too much about the obesity effect of GLP-1, we might taint a very good diabetes drug. (As noted earlier, Sorensen also viewed obesity as a social rather than a medical challenge.) Unexpected high discontinuation rate: Perhaps the most striking fact I learned from all of these podcasts was the exceptionally high discontinuation rate from GLP-1 medicines

12-14 The presence of adverse gastrointestinal symptoms (nausea, vomiting, dyspepsia, abdominal distension) in patients taking GLP-1 agonists are predictive of increased residual gastric contents

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Supporting overall wellness while taking GLP-1 medications can include lifestyle changes and nutritional support