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The American Society of Anesthesiologists recommended in June 2023 that patients stop taking GLP-1 agonists a week before elective surgeries, due to the increased risk of vomiting during surgery, while CNN reported in July other accounts of patients taking Ozempic and Wegovy suffering gastroparesis, with some claiming to have vomited days-old food

This finding ultimately led to the development of bremelanotide (Vyleesi), approved by the FDA in 2019 for hypoactive sexual desire disorder (HSDD) in premenopausal women

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