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They were then randomised to either continue Mounjaro or switch to a placebo

The primary skin-related effects are mild injection site reactions including redness, itching, and swelling at the subcutaneous injection site, which typically resolve within a few days

These are subsequently utilised as energy for the duration of exercise

Semaglutide and tirzepatide can help patients lose between 15% and 20% of their weight on average

doi:10.1177/2050313X251388724 Foscue E, et al

Baseline measurements should confirm AMPK suppression (reduced phosphorylation status in muscle or liver) and NAD+ depletion (low tissue NAD+ levels or elevated NNMT enzymatic activity)