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Nat Rev Nephrol (2020) 16(9):489508

The FDA's 503A framework also requires bulk substances used by compounders to meet applicable standards and be accompanied by a valid certificate of analysis, with the agency advising compounders to scrutinise their bulk-drug suppliers

Patients should be advised to seek prompt medical evaluation for severe or persistent gastrointestinal symptoms, vision changes, unusual neck swelling or hoarseness, or severe constipation with abdominal distention

10.1074/jbc.M116.756155 J

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