Excess skin can make it difficult to fully appreciate your weight loss results
doi: 10.1016/j.molimm.2007.12.025
Moreover, the mitochondrial dysfunction narrative still leaves unresolved the insulin sensitizers riddle, whereby anti-diabetic agents that promote sensitization to insulin e.g., biguanides / metformin, thiazolidinedioones / pioglitazone, high-dose aspirin, berberine and others, are all reported to act as mitochondrial complex I inhibitors [84], implying that mitochondrial dysfunction is more of a solution rather than a problem in the T2D context [85]
Godoy-Matos AF, Silva Junior WS, Valerio CM
Some studies report subjective improvements in sleep quality, energy, and mood
Patients are left navigating menus that were never designed for this new way of eating