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The -subunit of hCG has a highly glycosylated 24-amino acid C-terminal tail absent from LH, which increases receptor activity and slows metabolic clearance resulting in a half-life of approximately 36 hours for hCG compared to just 30 minutes for LH, making hCG an extended-duration pharmacological analogue of LH for receptor biology research

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Boku S, Nakagawa S, Toda H, Hishimoto A

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