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Over the past twenty years, the incidence of gout has nearly doubled, likely connected to an increase in obesity in the general population

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J Neurol 254(12):16761683 Kumar P, Kalonia H, Kumar A (2010) Nitric oxide mechanism in the protective effect of antidepressants against 3-nitropropionic acid-induced cognitive deficit, glutathione and mitochondrial alterations in animal model of Huntingtons disease